Crystals And Catalysts

A new report featuring in the February 2016 issue of  The FASEB Journal , scientists show that a gene called "DISC1," is believed to play a role in mental health disorders, such as schizophrenia, bipolar disorder (and other forms of depression); influence the function of pancreatic beta cells which produce insulin to maintain normal blood glucose levels. Understanding how the different mechanisms  of diseases in the body is essential to be able to pick efficient therapies for patients. Bortell and colleagues decided to study the function of DISC1 by comparing 2 groups of mice. The first group was genetically manipulated to disrupt the DISC1 gene only in the mouse's pancreatic beta cells. The second group of mice was normal. The mice with disrupted DISC1 gene showed increased beta cell death, less insulin secretion and impaired glucose regulation while control mice were normal. The researchers found that DISC1 works by controlling the activity of a specific protei...

W e haven't quite forgotten the ebola virus and a new virus has appeared under the spotlight; the Zika virus. The Zika virus is spread by mosquitos, similar in a way to malaria. However, unlike other mosquito-borne diseases, it is relatively unknown and little studied. The virus is currently showing an alarming rise in cases in Latin America and the Caribbean.  The virus has also  been associated with an alarming rise in babies born in Brazil with abnormally small heads and brain defects -- a condition called microcephaly.  Zika is spread by the same mosquito as the dengue virus: Aedes aegypti. Dengue is a serious disease but it doesn't usually kill people, whereas, Zika, is much more serious in that it is able to pass through a woman's placenta and impact the unborn child.  Since the Zika outbreak began in northeastern Brazil last spring, an estimated 500,000 to 1.5 million people have been infected. The resulting illness only lasts a few days. The sympt...

This blog post was previously titled: Females are less prone to influenza than males, thanks to Estrogen.  E strogen and its derivatives have been found to protect against respiratory infections such as influenza, in females more than males. This new study was published in the American Journal of Physiology-- Lung Cellular and Physiology. A virus usually works/makes you ill by invading a cell in your body and making and replicating itself within the host cell. After being released from the host cell, the virus can go on to infect other cells in the body and also other people.   The less a virus replicates, the less severe the infection and the lower the risk it will be spread onto other people. The researchers used human nasal epithelial cells (hNECs) from male and female donors- which are the main cells which the flu virus targets - and exposed the nasal cells to  17β-estradiol   (i.e estrogen) or select estrogen modulators (SERMs) (these include na...

Dan Perlman, a biophysicist, and K.C Hayes, a nutritionist,  have previously  developed the "healthy fats" blend in the Smart Balance buttery spread over twenty years ago; have now invented the parbaked coffee bean. This new method of roasting green coffee beans is meant to enhance the health benefits of coffee. Perlman developed the flour milled from parbaked beans to act as both a food ingredient and a nutritional supplement.  Many studies have proven that drinking coffee is good for you and I've written several posts on coffee in the past  here , here , here and here :) Perlman wanted to study a way to roast coffee beans but at the same time not loose its health benefits. When coffee beans are roasted at over  400 degrees Fahrenheit for 10 to 15 minutes -- the CGA content drops dramatically. One study found the decrease ranged from 50 to nearly 100 percent. Chlorogenic acid (CGA)is an antioxidant. CGA is thought to be beneficial in controllin...

The elements 113, 115, 117 and 118 have finally been discovered.   Laboratories in Russia, the United States and Japan have made many claims over the  years  that they have discovered them. But it was only at the end of 2015 when the elements were finally given their  permanent  place in the periodic table. A group of scientific experts at  The International Union of Pure and Applied Chemistry (IUPAC), headquartered in Research Triangle Park, North Carolina,  announced the group’s conclusions  on 30 December 2015. The four elements were made in the lab, by colliding  lighter atomic nuclei together. The unstable agglomerations of protons and neutrons lasted mere fractions of a second before they fell apart into smaller, more stable fragments. Each of the teams have been given recognition for their great findings which means that now, they can  put forward proposals  to name the new elements and assign them the...

Today's final post in the series will be on the science behind Santa's sleigh. Scientists at the North Carolina State University have analyzed and researched how Santa is using the latest scientific resources and technologies on his sleigh (that aren't scientifically available to us yet) to deliver everyone's Christmas presents. To deliver all the presents on time Santa's sleigh has to be a million times more advanced than any modern form of air transportation . The truss of the sleigh, including the runners, are made of a honeycombed titanium alloy that is very lightweight and 10 to 20 times stronger than anything that exists or that's being worked on in labs today. But it  doesn't  just stop there....  The truss can also morph, changing its shape slightly to improve its aerodynamics – allowing it to cut through the air more efficiently. The runners on the sleigh, for example, are a little bit flexible; this allows the runners to be tucked in ...

It's the day before Christmas eve, so Christmas preparations are well under way. Who will be making homemade eggnog this holiday season? And will you be "spiking" it? If you will, beware of the risk of salmonella in raw eggs.  With a statistic of 1/20000 eggs is contaminated with salmonella bacteria drinking homemade eggnog can be a bit of a hefty risk. Scientists at Rockefeller University conducted an experiment on eggnog and spiked eggnog (with alcohol added to it =  20 percent rum and bourbon) to compare the  bacteria found in homemade alcoholic eggnog with those found in store-bought nonalcoholic eggnog. After culturing samples of both solutions and incubating them for 24 hours at 37 degrees Celsius (body temperature), The researchers found that while the store-bought product was brimming with a variety of bacteria, the homemade version was completely sterile. “The bacteria we observed in the grocery-store product are likely harmless normal bacteria that ...

Today's post is based around candy canes - but not candy canes exactly, more like Christmas sweets including licorice. Scientists have found that a novel molecule extracted from licorice root has the ability to stop some cancers immediately, according to a collaborative research study conducted at Rutgers, The State University of New Jersey.  Mohamed Rafi, assistant professor in the department of food science at Rutgers' Cook College, discovered the new molecule, ß-hydroxy-DHP (BHP), in common dietary supplements made from licorice root, a natural remedy with curative powers which have gone down in history. Rafi tested the compound in the laboratory on tissues taken from prostate and breast cancer tumors. The small and very specific molecule BHP  belongs to a class of organic chemicals known as polyphenols that include potential anticancer compounds found in green tea and wine; its main target is cancer cells. It works by deactivat...

Today's post will be on walnuts. Walnuts also constitute a part of the Christmas platter and they're also good for you. Most of the health benefits of walnuts are known already but scientists have found one more to add to the list: lowering of diabetes and heart disease risk in "at-risk" patients.  The research was published in the  Journal of the American College of Nutrition , the Official Publication of the American College of Nutrition, and a publication from Routledge. For the study, a sample of 46 adults aged 30-75 were selected. Participants had a Body Mass Index larger than 25, and a waist circumference exceeding 40 inches for men and 35 inches for women. They were also required to be non-smokers, and all exhibited one or more additional risk factors for metabolic syndrome, a precursor of diabetes and cardiovascular disease. The group was randomly assigned to two 8-week sequences of either ...

Every year baubles get more innovative from your typical gold and sliver baubles to solar system themed baubles and finally gold and silver nano-baubles. The nano-baubles produced by researchers, in Mexico and the US, are about 100 million times smaller than the typical baubles which are used to decorate Christmas trees. The research was published December 2010 i ssue of the  International Journal of Nanoparticles , where the  scientists  reported the formation of various sliver, gold and bimetallic nanoparticles which are only 25 nanometres in diameter.  They  utilized  vitamin C (a.k.a ascorbic acid) and a soap like antiseptic which is usually used in high-end cosmetics. The reaction of silver nitrate and the  gold compound chloroauric acid under these conditions led to successive reduction of the metals and the formation of different silver, gold and bimetallic nanoparticles. The precise structures of the nanoparticles were rev...